Novel Surface Antigen that Promotes the Dissemination of Pancreatic Cancer Cells through Regulation of Cathepsins B and D

Laurent Dumartin, Hannah J Whiteman, Mark E Weeks, Deepak Hariharan, Branko Dmitrovic, Christine A Iacobuzio-Donahue, Teresa A Brentnall, Mary P Bronner, Roger M Feakins, John F Timms, Caroline Brennan, Nicholas R Lemoine and Tatjana CrnogoracJurcevic Centre for Molecular Oncology, Barts Cancer Institute, Queen Mary University of London, London EC1M 6BQ, UK Proteomics, Metabolomics and Bioimaging, AHVLA-Weybridge, Addlestone KT15 3NB, UK Department of Pathology and Forensic Medicine, KBC Osijek, 31000 Osijek, Croatia Department of Pathology, The Sol Goldman Pancreatic Cancer Research Center, Johns Hopkins Medical Institutions, Baltimore, Maryland 21231, USA Division of Gastroenterology, Department of Medicine, University of Washington, Seattle, Washington 98195, USA Department of Anatomic Pathology, University of Utah, Salt Lake City, Utah 84108, USA Department of Histopathology, Royal London Hospital, London E1 1BB, UK Cancer Proteomics Laboratory, EGA Institute for Women's Health, University College London, Gower Street, London WC1E 6BT, UK School of Biological and Chemical Sciences, Queen Mary University of London, London E1 4NS, UK Short title: AGR2 in pancreatic cancer invasion